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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2153
http://purl.obolibrary.org/obo/NCIT_C2153
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|---|---|
| Preferred Name | Dihydrofolate Reductase Inhibitor |
| Definitions |
Any substance that inhibits dihydrofolate reductase, an enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate, an essential reaction for de novo glycine and purine synthesis. Inhibition of dihydrofolate reductase interferes with DNA and protein synthesis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Any substance that inhibits dihydrofolate reductase, an enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate, an essential reaction for de novo glycine and purine synthesis. Inhibition of dihydrofolate reductase interferes with DNA and protein synthesis. |
|---|---|
| prefLabel | Dihydrofolate Reductase Inhibitor
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| label | Dihydrofolate Reductase Inhibitor
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| code | C2153
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| prefixIRI | NCIT:C2153
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| Preferred_Name | Dihydrofolate Reductase Inhibitor
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| Legacy Concept Name | Dihydrofolate_Reductase_Inhibitor
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| type | |
| subClassOf | |
| Semantic_Type | Chemical Viewed Functionally
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| UMLS_CUI | C3537100
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