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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C21254
http://purl.obolibrary.org/obo/NCIT_C21254
|
|---|---|
| Preferred Name | E3 Ubiquitin-Protein Transferase |
| Definitions |
An ATP-dependent aminoacyltransferase that catalyzes the third step in the ubiquitination reaction via the transfer of ubiquitin from an E2 ubiquitin-conjugating enzyme to lysine residues found in the final substrate protein.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An ATP-dependent aminoacyltransferase that catalyzes the third step in the ubiquitination reaction via the transfer of ubiquitin from an E2 ubiquitin-conjugating enzyme to lysine residues found in the final substrate protein. |
|---|---|
| prefLabel | E3 Ubiquitin-Protein Transferase
|
| label | E3 Ubiquitin-Protein Transferase
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| NCI_META_CUI | CL449066
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| code | C21254
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| prefixIRI | NCIT:C21254
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| Preferred_Name | E3 Ubiquitin-Protein Transferase
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| Legacy Concept Name | E3_Ubiquitin_Ligase
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| DesignNote | The IUBMB has recategorized E3 ubiquitin-protein ligases as transferases (EC 2). There are 2 categories of E3 enzymes based on the structure of the active site: HECT-type (EC 2.3.2.26) and RING-type (EC 2.3.2.27).
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
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