Preferred Name

Alpha Adrenergic Receptor

Synonyms
Definitions

Expressed by Alpha Adrenergic Receptor Genes in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Alpha Adrenergic Receptors are one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Alpha-adrenergic receptors respond to blocking agents such as phenoxybenzamine and phentolamine. When coupled to adenylate cyclase through Gi protein, Alpha Adrenergic Receptor stimulation results in decreased intracellular cyclic AMP.

ID

http://purl.obolibrary.org/obo/NCIT_C20932

code

C20932

Contributing_Source

CTRP

definition

Expressed by Alpha Adrenergic Receptor Genes in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Alpha Adrenergic Receptors are one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Alpha-adrenergic receptors respond to blocking agents such as phenoxybenzamine and phentolamine. When coupled to adenylate cyclase through Gi protein, Alpha Adrenergic Receptor stimulation results in decreased intracellular cyclic AMP.

Display_Name

Alpha Adrenergic Receptor

in_subset

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C142800

http://purl.obolibrary.org/obo/NCIT_C142799

label

Alpha Adrenergic Receptor

Legacy Concept Name

Alpha_Adrenergic_Receptor

Preferred_Name

Alpha Adrenergic Receptor

prefixIRI

NCIT:C20932

prefLabel

Alpha Adrenergic Receptor

Semantic_Type

Amino Acid, Peptide, or Protein

Receptor

UMLS_CUI

C0034784

subClassOf

http://purl.obolibrary.org/obo/NCIT_C18239

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