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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C20931
http://purl.obolibrary.org/obo/NCIT_C20931
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|---|---|
| Preferred Name | Baculoviral IAP Repeat-Containing Protein 2 |
| Definitions |
Baculoviral IAP repeat-containing protein 2 (618 aa, ~70 kDa) is encoded by the human BIRC2 gene. This protein plays a role in the regulation of apoptosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Baculoviral IAP repeat-containing protein 2 (618 aa, ~70 kDa) is encoded by the human BIRC2 gene. This protein plays a role in the regulation of apoptosis. |
|---|---|
| prefLabel | Baculoviral IAP Repeat-Containing Protein 2
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| label | Baculoviral IAP Repeat-Containing Protein 2
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| code | C20931
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| prefixIRI | NCIT:C20931
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| OMIM_Number | 601712
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| in_subset | |
| Display_Name | Baculoviral IAP Repeat-Containing Protein 2
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| Preferred_Name | Baculoviral IAP Repeat-Containing Protein 2
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| Contributing_Source | CTRP
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| Swiss_Prot | Q13490
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| Legacy Concept Name | Baculoviral_IAP_Repeat-Containing_Protein-2
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| DesignNote | Encoded by BIRC2 Gene (IAP Family), Baculoviral IAP Repeat-Containing Protein 2 inhibits apoptosis by binding to TNF Receptor-associated factors TRAF1 and TRAF2 preventing activation of ICE-like proteases. BIRC2 inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain.
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| type | |
| subClassOf | |
| Semantic_Type | Amino Acid, Peptide, or Protein
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| UMLS_CUI | C1531411
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