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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2088
http://purl.obolibrary.org/obo/NCIT_C2088
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|---|---|
| Preferred Name | Ornithine Decarboxylase Inhibitor |
| Definitions |
Any substance that inhibits ornithine decarboxylase, an enzyme that catalyzes the decarboxylation of ornithine, the rate-limiting, commiting reaction in polyamine synthesis. Polyamines are important for stabilizing DNA structure, for the DNA double strand-break repair pathway, and as antioxidants, and inhibition of ornithine decarboxylase inhibits cell growth.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Any substance that inhibits ornithine decarboxylase, an enzyme that catalyzes the decarboxylation of ornithine, the rate-limiting, commiting reaction in polyamine synthesis. Polyamines are important for stabilizing DNA structure, for the DNA double strand-break repair pathway, and as antioxidants, and inhibition of ornithine decarboxylase inhibits cell growth. |
|---|---|
| prefLabel | Ornithine Decarboxylase Inhibitor
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| label | Ornithine Decarboxylase Inhibitor
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| code | C2088
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| prefixIRI | NCIT:C2088
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| Preferred_Name | Ornithine Decarboxylase Inhibitor
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| Legacy Concept Name | Ornithine_Decarboxylase_Inhibitor
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| type | |
| subClassOf | |
| Semantic_Type | Chemical Viewed Functionally
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| UMLS_CUI | C1518618
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