Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Stefin Family Gene
Synonyms
Definitions

One of three inhibitory families in the cystatin superfamily (including type 2 cystatins and kininogens), Stefin Family Genes (type 1 cystatins) encode intracellular cysteine thiol protease inhibitors of papain and cathepsins B, H, and L. Cystatin Superfamily proteins contain multiple cystatin-like sequences; some are active cysteine protease inhibitors, while others have lost or perhaps never acquired this activity. (NCI)
ID

http://purl.obolibrary.org/obo/NCIT_C20729
code

C20729
definition

One of three inhibitory families in the cystatin superfamily (including type 2 cystatins and kininogens), Stefin Family Genes (type 1 cystatins) encode intracellular cysteine thiol protease inhibitors of papain and cathepsins B, H, and L. Cystatin Superfamily proteins contain multiple cystatin-like sequences; some are active cysteine protease inhibitors, while others have lost or perhaps never acquired this activity. (NCI)
label

Stefin Family Gene
Legacy Concept Name

Stefin_Family_Gene
Preferred_Name

Stefin Family Gene
prefixIRI

NCIT:C20729
prefLabel

Stefin Family Gene
Semantic_Type

Gene or Genome
UMLS_CUI

C1336499
subClassOf

http://purl.obolibrary.org/obo/NCIT_C20726
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