Preferred Name

Fibroblast Growth Factor 1

Synonyms
Definitions

Fibroblast growth factor 1 (17 aa, ~155 kDa) is encoded by the human FGF1 gene. This protein plays a role in cell proliferation, angiogenesis, cell differentiation, and cell migration.

ID

http://purl.obolibrary.org/obo/NCIT_C20548

code

C20548

Contributing_Source

CTRP

definition

Fibroblast growth factor 1 (17 aa, ~155 kDa) is encoded by the human FGF1 gene. This protein plays a role in cell proliferation, angiogenesis, cell differentiation, and cell migration.

DesignNote

Fibroblast growth factor 1 lacks a cleavable signal sequence; it is transported through the cytoplasm to the cell membrane and then secreted by a non-classical pathway that requires Cu2+ ions and protein S100-A13. (UniProt)

Display_Name

Fibroblast Growth Factor 1

in_subset

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C142800

http://purl.obolibrary.org/obo/NCIT_C142799

label

Fibroblast Growth Factor 1

Legacy Concept Name

Fibroblast_Growth_Factor-1

OMIM_Number

131220

Preferred_Name

Fibroblast Growth Factor 1

prefixIRI

NCIT:C20548

prefLabel

Fibroblast Growth Factor 1

Semantic_Type

Amino Acid, Peptide, or Protein

Swiss_Prot

P05230

UMLS_CUI

C0079349

subClassOf

http://purl.obolibrary.org/obo/NCIT_C20426

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