loading...| Preferred Name |
Tumor Necrosis Factor |
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| Synonyms |
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| Definitions |
Tumor necrosis factor (233 aa, ~26 kDa) is encoded by the human TNF gene. This protein is involved in the induction of cytokine expression, the stimulation of cell proliferation and the positive regulation of cell differentiation. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C20535 |
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| code |
C20535 |
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| Contributing_Source |
CTRP |
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| definition |
Tumor necrosis factor (233 aa, ~26 kDa) is encoded by the human TNF gene. This protein is involved in the induction of cytokine expression, the stimulation of cell proliferation and the positive regulation of cell differentiation. |
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| DesignNote |
Tumor necrosis factor (TNF) is a serum glycoprotein produced by activated macrophages and other mammalian mononuclear leukocytes which has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. |
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| Display_Name |
Tumor Necrosis Factor |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C116977 |
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| label |
Tumor Necrosis Factor |
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| Legacy Concept Name |
Tumor_Necrosis_Factor-Alpha |
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| OMIM_Number |
191160 |
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| Preferred_Name |
Tumor Necrosis Factor |
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| prefixIRI |
NCIT:C20535 |
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| prefLabel |
Tumor Necrosis Factor |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Immunologic Factor |
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| Swiss_Prot |
P01375 |
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| UMLS_CUI |
C1448177 |
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| subClassOf |