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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C20521
http://purl.obolibrary.org/obo/NCIT_C20521
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|---|---|
| Preferred Name | Interleukin-1 Alpha |
| Definitions |
Interleukin-1 alpha (271 aa, ~31 kDa) is encoded by the human IL1A gene. This protein is involved in B-cell maturation and proliferation, thymocyte proliferation and the stimulation of inflammation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Interleukin-1 alpha (271 aa, ~31 kDa) is encoded by the human IL1A gene. This protein is involved in B-cell maturation and proliferation, thymocyte proliferation and the stimulation of inflammation. |
|---|---|
| label | Interleukin-1 Alpha
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| prefLabel | Interleukin-1 Alpha
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| Legacy Concept Name | Interleukin-1-Alpha
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| in_subset | |
| Preferred_Name | Interleukin-1 Alpha
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| Display_Name | Interleukin-1 Alpha
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| Swiss_Prot | P01583
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| UMLS_CUI | C1702299
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| prefixIRI | NCIT:C20521
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| Contributing_Source | CTRP
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| subClassOf | |
| code | C20521
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| type | |
| ALT_DEFINITION | One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-1-alpha, one form of IL-1, is made mainly by one type of white blood cell, the macrophage, and helps another type of white blood cell, the lymphocyte, fight infections. It also helps leukocytes pass through blood vessel walls to sites of infection and causes fever by affecting areas of the brain that control body temperature. The other form of IL-1, IL-1-beta, acts the same as IL-1-alpha. IL-1-alpha made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. IL-1-alpha is a type of cytokine.
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| OMIM_Number | 147760
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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