loading...| Preferred Name |
Interleukin-8 |
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| Synonyms |
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| Definitions |
Interleukin-8 (99 aa, ~11 kDa) is encoded by the human CXCL8 gene. This protein is involved in chemotaxis and neutrophil activation. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C20473 |
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| code |
C20473 |
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| Contributing_Source |
CTRP |
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| definition |
Interleukin-8 (99 aa, ~11 kDa) is encoded by the human CXCL8 gene. This protein is involved in chemotaxis and neutrophil activation. |
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| DesignNote |
Interleukin-8 is cleaved into the following seven chains: MDNCF-a (GCP/IL-8 protein IV, IL8/NAP1 form I), Interleukin-8 ((Ala-IL-8)77, GCP/IL-8 protein II, IL-8(1-77), IL8/NAP1 form II, MDNCF-b), IL-8(5-77), IL-8(6-77) ((Ser-IL-8)72, GCP/IL-8 protein I, IL8/NAP1 form III, lymphocyte-derived neutrophil-activating factor, LYNAP, MDNCF-c, neutrophil-activating factor, NAF), IL-8(7-77) (GCP/IL-8 protein V, IL8/NAP1 form IV), IL-8(8-77) (GCP/IL-8 protein VI, IL8/NAP1 form V), and IL-8(9-77) (GCP/IL-8 protein III; IL8/NAP1 form VI). (UniProt) |
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| Display_Name |
Interleukin-8 |
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| in_subset |
http://purl.obolibrary.org/obo/NCIT_C116977 |
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| label |
Interleukin-8 |
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| Legacy Concept Name |
Interleukin-8 |
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| OMIM_Number |
146930 |
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| Preferred_Name |
Interleukin-8 |
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| prefixIRI |
NCIT:C20473 |
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| prefLabel |
Interleukin-8 |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Immunologic Factor |
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| Swiss_Prot |
P10145 |
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| UMLS_CUI |
C1698756 |
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| subClassOf |