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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C20473
http://purl.obolibrary.org/obo/NCIT_C20473
|
|---|---|
| Preferred Name | Interleukin-8 |
| Definitions |
Interleukin-8 (99 aa, ~11 kDa) is encoded by the human CXCL8 gene. This protein is involved in chemotaxis and neutrophil activation.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Interleukin-8 (99 aa, ~11 kDa) is encoded by the human CXCL8 gene. This protein is involved in chemotaxis and neutrophil activation. |
|---|---|
| prefLabel | Interleukin-8
|
| label | Interleukin-8
|
| code | C20473
|
| prefixIRI | NCIT:C20473
|
| OMIM_Number | 146930
|
| in_subset | |
| Display_Name | Interleukin-8
|
| Preferred_Name | Interleukin-8
|
| Contributing_Source | CTRP
|
| Swiss_Prot | P10145
|
| Legacy Concept Name | Interleukin-8
|
| DesignNote | Interleukin-8 is cleaved into the following seven chains: MDNCF-a (GCP/IL-8 protein IV, IL8/NAP1 form I), Interleukin-8 ((Ala-IL-8)77, GCP/IL-8 protein II, IL-8(1-77), IL8/NAP1 form II, MDNCF-b), IL-8(5-77), IL-8(6-77) ((Ser-IL-8)72, GCP/IL-8 protein I, IL8/NAP1 form III, lymphocyte-derived neutrophil-activating factor, LYNAP, MDNCF-c, neutrophil-activating factor, NAF), IL-8(7-77) (GCP/IL-8 protein V, IL8/NAP1 form IV), IL-8(8-77) (GCP/IL-8 protein VI, IL8/NAP1 form V), and IL-8(9-77) (GCP/IL-8 protein III; IL8/NAP1 form VI). (UniProt)
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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| UMLS_CUI | C1698756
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