loading...| Preferred Name | Platelet-Derived Growth Factor | |
| Synonyms |
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| Definitions |
A family of growth factors that act as potent mitogens and are involved in the stimulation of angiogenesis. There are four members of this family (platelet-derived growth factor A, B, C and D) that are characterized by a core motif of eight cysteines. They bind to their cognate receptor tyrosine kinases (platelet-derived growth factor receptor family) as homodimers or heterodimers to stimulate signaling. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C20448 |
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| ALT_DEFINITION |
A family of molecules released from platelets (tiny pieces of cells that are found in the blood and that help the blood clot). Forms of PDGF help to heal wounds and to repair damage to blood vessel walls. They also help blood vessels grow. |
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| code |
C20448 |
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| definition |
A family of growth factors that act as potent mitogens and are involved in the stimulation of angiogenesis. There are four members of this family (platelet-derived growth factor A, B, C and D) that are characterized by a core motif of eight cysteines. They bind to their cognate receptor tyrosine kinases (platelet-derived growth factor receptor family) as homodimers or heterodimers to stimulate signaling. |
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| DesignNote |
Vascular endothelial growth factors are considered a subfamily of the platelet-derived growth factor family. |
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| label |
Platelet-Derived Growth Factor |
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| Legacy Concept Name |
Platelet-Derived_Growth_Factor |
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| Preferred_Name |
Platelet-Derived Growth Factor |
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| prefixIRI |
NCIT:C20448 |
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| prefLabel |
Platelet-Derived Growth Factor |
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| Semantic_Type |
Amino Acid, Peptide, or Protein |
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| UMLS_CUI |
C0032200 |
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| subClassOf |