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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C20428
http://purl.obolibrary.org/obo/NCIT_C20428
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|---|---|
| Preferred Name | Hepatocyte Growth Factor |
| Definitions |
Hepatocyte growth factor (728 aa, ~83 kDa) is encoded by the human HGF gene. This protein is involved in both the modulation of hepatocyte proliferation and growth factor receptor signaling in hepatocytes and many other cell types.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Hepatocyte growth factor (728 aa, ~83 kDa) is encoded by the human HGF gene. This protein is involved in both the modulation of hepatocyte proliferation and growth factor receptor signaling in hepatocytes and many other cell types. |
|---|---|
| prefLabel | Hepatocyte Growth Factor
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| label | Hepatocyte Growth Factor
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| code | C20428
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| prefixIRI | NCIT:C20428
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| OMIM_Number | 142409
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| in_subset | |
| Display_Name | Hepatocyte Growth Factor
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| Preferred_Name | Hepatocyte Growth Factor
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| Contributing_Source | CTRP
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| Swiss_Prot | P14210
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| Legacy Concept Name | Hepatocyte_Growth_Factor
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| DesignNote | Hepatocyte growth factor is secreted as a single chain polypeptide, which is cleaved by serine proteases. The cleaved growth factor is a heterodimer comprised of disulfide bonded alpha- and beta-chains. (EntrezGene and UniProt)
Hepatocyte growth factor resembles S1 family peptidases. It has 4 kringle domains and an inactive S1 peptidase domain. (UniProt)
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| type | |
| subClassOf | |
| Semantic_Type | Amino Acid, Peptide, or Protein
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| UMLS_CUI | C1447107
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