Preferred Name |
Transcription Factor Gene |
|
Synonyms |
|
|
Definitions |
Genes that code for transcription factors. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C20420 |
|
code |
C20420 |
|
definition |
Genes that code for transcription factors. |
|
DesignNote |
Initiation of transcription from eukaryotic protein-coding genes is a complex process requiring RNA polymerase II (Pol II) and a cadre of transcription factors. These factors can be divided into 2 classes on the basis of their function: the general factors that are required for transcription of all Pol II genes, and sequence-specific factors that are required for regulating expression. The general transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promoter elements. The most common core element is the TATA box, typically located 25-30 bp upstream of the transcriptional start site or initiator element. Sequence-specific transcription factors that bind to DNA-sequence elements located proximal and distal to the core promoter elements can dramatically enhance or repress transcription. (from OMIM 189962) |
|
Gene_Encodes_Product |
Transcription Factor |
|
label |
Transcription Factor Gene |
|
Legacy Concept Name |
Transcription_Factor_Gene |
|
Preferred_Name |
Transcription Factor Gene |
|
prefixIRI |
NCIT:C20420 |
|
prefLabel |
Transcription Factor Gene |
|
Semantic_Type |
Gene or Genome |
|
UMLS_CUI |
C0812327 |
|
subClassOf |
Delete | Mapping To | Ontology | Source |
---|---|---|---|
http://purl.obolibrary.org/obo/NCIT_C20420 | GSSO | SAME_URI | |
http://www.projecthalo.com/aura#Transcription-Factor-Gene | AURA | LOOM | |
http://purl.obolibrary.org/obo/NCIT_C20420 | GSSO | LOOM | |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C20420 | NCIT | LOOM |