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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C20214
http://purl.obolibrary.org/obo/NCIT_C20214
|
|---|---|
| Preferred Name | Hypoxia-Inducible Factor 1-Alpha |
| Definitions |
Hypoxia-inducible factor 1-alpha (826 aa, ~93 kDa) is encoded by the human HIF1A gene. This protein plays a role in transcriptional regulation in response to hypoxia.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Hypoxia-inducible factor 1-alpha (826 aa, ~93 kDa) is encoded by the human HIF1A gene. This protein plays a role in transcriptional regulation in response to hypoxia. |
|---|---|
| prefLabel | Hypoxia-Inducible Factor 1-Alpha
|
| label | Hypoxia-Inducible Factor 1-Alpha
|
| code | C20214
|
| prefixIRI | NCIT:C20214
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| OMIM_Number | 603348
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| in_subset | |
| Display_Name | Hypoxia-Inducible Factor 1-Alpha
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| Preferred_Name | Hypoxia-Inducible Factor 1-Alpha
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| Contributing_Source | CTRP
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| Swiss_Prot | Q16665
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| Legacy Concept Name | Hypoxia-Inducible_Factor-1_Alpha_Subunit
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| DesignNote | Under normoxic conditions, HIF-1alpha is rapidly degraded, whereas hypoxia, CoCl(2), or desferroxamine promote protein stabilization, thus evoking its transcriptional activity.
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| type | |
| subClassOf | |
| Semantic_Type | Amino Acid, Peptide, or Protein
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| UMLS_CUI | C1528322
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