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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C20209
http://purl.obolibrary.org/obo/NCIT_C20209
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|---|---|
| Preferred Name | Epithelial Cell Adhesion Molecule |
| Definitions |
Epithelial cell adhesion molecule (314 aa, ~35 kDa) is encoded by the human EPCAM gene. This protein is involved in both cell adhesion and cellular proliferation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Epithelial cell adhesion molecule (314 aa, ~35 kDa) is encoded by the human EPCAM gene. This protein is involved in both cell adhesion and cellular proliferation. |
|---|---|
| prefLabel | Epithelial Cell Adhesion Molecule
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| label | Epithelial Cell Adhesion Molecule
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| code | C20209
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| prefixIRI | NCIT:C20209
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| OMIM_Number | 185535
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| in_subset | |
| Display_Name | Epithelial Cell Adhesion Molecule
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| Preferred_Name | Epithelial Cell Adhesion Molecule
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| Contributing_Source | CTRP
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| Swiss_Prot | P16422
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| Legacy Concept Name | Tumor-Associated_Calcium_Signal_Transducer-1
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| DesignNote | Ep-CAM is a cell adhesion molecule expressed in epithelial cells and a ligand for leukocyte-associated immunoglobulin-like receptor 1 (LAIR1). Ep-CAM also binds to LAIR2. Ep-CAM may act to prevent an excessive inflammatory response. Over expression of Ep-CAM in breast cancer may be correlated with the histologic grade of the disease and a predictor of poor prognosis. (from OMIM 600718)
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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| UMLS_CUI | C0903677
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