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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2020
http://purl.obolibrary.org/obo/NCIT_C2020
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|---|---|
| Preferred Name | Farnesyl Transferase Inhibitor |
| Definitions |
Any substance that inhibits protein farnesyltransferase, an enzyme that catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine. Protein farnesyltransferase is involved in Ras-mediated post-translational modification. Inhibition of protein farnesyltransferase may inhibit the oncogenic activity of Ras.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Any substance that inhibits protein farnesyltransferase, an enzyme that catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine. Protein farnesyltransferase is involved in Ras-mediated post-translational modification. Inhibition of protein farnesyltransferase may inhibit the oncogenic activity of Ras. |
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| prefLabel | Farnesyl Transferase Inhibitor
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| label | Farnesyl Transferase Inhibitor
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| CHEBI_ID | CHEBI:64133
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| code | C2020
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| prefixIRI | NCIT:C2020
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| Preferred_Name | Farnesyl Transferase Inhibitor
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| Legacy Concept Name | Farnesyl_Transferase_Inhibitor
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| type | |
| subClassOf | |
| Semantic_Type | Chemical Viewed Functionally
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| UMLS_CUI | C1517132
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