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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C2019
http://purl.obolibrary.org/obo/NCIT_C2019
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|---|---|
| Preferred Name | Dihydropyrimidine Dehydrogenase Inhibitor |
| Definitions |
Any substance that inhibits dihydropyrimidine dehydrogenase, a rate limiting enzyme in the degradation of pyrimidines. Inhibition of dihydropyrimidine dehydrogenase increases the biological half-life and efficacy of 5-Fluorouracil (5-FU).
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Any substance that inhibits dihydropyrimidine dehydrogenase, a rate limiting enzyme in the degradation of pyrimidines. Inhibition of dihydropyrimidine dehydrogenase increases the biological half-life and efficacy of 5-Fluorouracil (5-FU). |
|---|---|
| prefLabel | Dihydropyrimidine Dehydrogenase Inhibitor
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| label | Dihydropyrimidine Dehydrogenase Inhibitor
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| code | C2019
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| prefixIRI | NCIT:C2019
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| Preferred_Name | Dihydropyrimidine Dehydrogenase Inhibitor
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| Legacy Concept Name | Dihydropyrimidine_Dehydrogenase_Inhibitor
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| type | |
| subClassOf | |
| Semantic_Type | Chemical Viewed Functionally
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| UMLS_CUI | C1511962
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