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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C20037
http://purl.obolibrary.org/obo/NCIT_C20037
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|---|---|
| Preferred Name | FAK Family Tyrosine Kinase |
| Definitions |
Soluble cytoplasmic non-receptor FAK (Focal Adhesion Kinase) Family Tyrosine Kinases catalyze the phosphorylation of tyrosine residues in proteins with ATP or other nucleotides as phosphate donors. FAK is found in intracellular signaling focal adhesion complexes following engagement of the extracellular matrix by integrins. The C-terminal 'focal adhesion targeting' (FAT) region is necessary and sufficient for localizing FAK to focal adhesions.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Soluble cytoplasmic non-receptor FAK (Focal Adhesion Kinase) Family Tyrosine Kinases catalyze the phosphorylation of tyrosine residues in proteins with ATP or other nucleotides as phosphate donors. FAK is found in intracellular signaling focal adhesion complexes following engagement of the extracellular matrix by integrins. The C-terminal 'focal adhesion targeting' (FAT) region is necessary and sufficient for localizing FAK to focal adhesions. |
|---|---|
| prefLabel | FAK Family Tyrosine Kinase
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| label | FAK Family Tyrosine Kinase
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| code | C20037
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| prefixIRI | NCIT:C20037
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| Preferred_Name | FAK Family Tyrosine Kinase
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| Legacy Concept Name | FAK_Family_Tyrosine_Kinase
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
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| UMLS_CUI | C1333531
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