Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C1953
http://purl.obolibrary.org/obo/NCIT_C1953
Preferred Name

Recombinant Interferon Alfa-2b
Definitions
A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects.
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects.
prefLabel
Recombinant Interferon Alfa-2b
label
Recombinant Interferon Alfa-2b
PDQ_Closed_Trial_Search_ID
462279
code
C1953
Has_Target
prefixIRI
NCIT:C1953
in_subset
Display_Name
Recombinant Interferon Alfa-2b
Preferred_Name
Recombinant Interferon Alfa-2b
FDA_UNII_Code
43K1W2T1M6
Contributing_Source
CTRP
FDA
Maps_To
Recombinant Interferon Alfa-2b
CAS_Registry
98530-12-2
99210-65-8
NSC Number
377523
NCI_Drug_Dictionary_ID
462279
Legacy Concept Name
Recombinant_Interferon_Alfa-2b
type
ALT_DEFINITION
A drug used to treat some infections caused by viruses and several types of cancer. These include hairy cell leukemia, melanoma, and follicular lymphoma. It is a form of interferon alfa (a substance normally made by cells of the immune system) that is made in the laboratory. It is a type of biological response modifier.
Is_Value_For_GDC_Property
subClassOf
PDQ_Open_Trial_Search_ID
462279
Semantic_Type
Amino Acid, Peptide, or Protein
Pharmacologic Substance
UMLS_CUI
C0021735
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