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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1952
http://purl.obolibrary.org/obo/NCIT_C1952
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|---|---|
| Preferred Name | Recombinant Interferon Alfa-2a |
| Definitions |
A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A non-glycosylated recombinant human alpha interferon, subtype 2a, produced in the bacterium E. coli. Interferon alpha-2a binds to its specific cell-surface receptor, resulting in the transcription and translation of genes whose protein products have antiviral, antiproliferative, anticancer, and immune modulating effects. (NCI04) |
|---|---|
| label | Recombinant Interferon Alfa-2a
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| prefLabel | Recombinant Interferon Alfa-2a
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| Legacy Concept Name | Interferon_Alpha-2a
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| in_subset |
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| Preferred_Name | Recombinant Interferon Alfa-2a
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| Is_Value_For_GDC_Property | |
| Display_Name | Recombinant Interferon Alfa-2a
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| Maps_To | Recombinant Interferon Alfa-2a
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| PDQ_Open_Trial_Search_ID | 467189
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| UMLS_CUI | C0021734
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| FDA_UNII_Code | 47RRR83SK7
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| prefixIRI | NCIT:C1952
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| Accepted_Therapeutic_Use_For | Chronic phase Philadelphia chromosome-positive chronic myelogenous leukemia; hairy cell leukemia; chronic hepatitis C; AIDs-related Kaposis sarcoma; bladder; ovarian; cervical cancer; non-Hodgkins lymphoma; renal cell carcinoma; melanoma.
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| NCI_Drug_Dictionary_ID | 467189
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| Contributing_Source |
CTRP
FDA
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| subClassOf | |
| code | C1952
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| type | |
| NSC Number | 367982
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| PDQ_Closed_Trial_Search_ID | 467189
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
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| CAS_Registry | 76543-88-9
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