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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1946
http://purl.obolibrary.org/obo/NCIT_C1946
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|---|---|
| Preferred Name | Histone Deacetylase Inhibitor |
| Definitions |
Any substance that inhibits histone deacetylase, an enzyme that catalyzes the removal of acetyl groups from core histones. Inhibition of histone deacetylase can result in hyperacetylation of histones, with an effect on gene expression and cell differentiation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Any substance that inhibits histone deacetylase, an enzyme that catalyzes the removal of acetyl groups from core histones. Inhibition of histone deacetylase can result in hyperacetylation of histones, with an effect on gene expression and cell differentiation. |
|---|---|
| prefLabel | Histone Deacetylase Inhibitor
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| label | Histone Deacetylase Inhibitor
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| CHEBI_ID | CHEBI:61115
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| code | C1946
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| prefixIRI | NCIT:C1946
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| Preferred_Name | Histone Deacetylase Inhibitor
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| Legacy Concept Name | Histone_Deacetylase_Inhibitor
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| type | |
| ALT_DEFINITION | A substance that causes a chemical change that stops tumor cells from dividing. HDAC inhibitors are being studied in the treatment of cancer.
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| subClassOf | |
| Semantic_Type | Chemical Viewed Functionally
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| UMLS_CUI | C1512474
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