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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1928
http://purl.obolibrary.org/obo/NCIT_C1928
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|---|---|
| Preferred Name | Dynemicin |
| Definitions |
An antitumor antibiotic of the enediyne class. It has demonstrated high DNA cleavage activity in the presence of NADPH, antimicrobial and tumor growth-inhibiting properties. Dynemicin recognizes and cleaves conformationally flexible regions of DNA. It attacks bases at 3'-side of purine residues such as 5'-AG, 5'-AT, and 5'-GC sequences. (NCI)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An antitumor antibiotic of the enediyne class. It has demonstrated high DNA cleavage activity in the presence of NADPH, antimicrobial and tumor growth-inhibiting properties. Dynemicin recognizes and cleaves conformationally flexible regions of DNA. It attacks bases at 3'-side of purine residues such as 5'-AG, 5'-AT, and 5'-GC sequences. (NCI) |
|---|---|
| prefLabel | Dynemicin
|
| label | Dynemicin
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| code | C1928
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| prefixIRI | NCIT:C1928
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| in_subset | |
| Preferred_Name | Dynemicin
|
| Maps_To | Dynemicin
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| Legacy Concept Name | Dynemicin
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Antibiotic
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| UMLS_CUI | C1512097
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