Preferred Name

B-Cell Activation
Synonyms
Definitions

A set of events occurring in B lymphocytes following stimulation with cognate antigen. Crosslinking the B cell antigen receptor (surface immunoglobulin) leads to increased expression of MHC class II molecules, exit from the resting state (G0) into the G1 phase of the cell cycle, and in the case of a strong antigenic stimulus, proliferation.

ID

http://purl.obolibrary.org/obo/NCIT_C19255

code

C19255

definition

A set of events occurring in B lymphocytes following stimulation with cognate antigen. Crosslinking the B cell antigen receptor (surface immunoglobulin) leads to increased expression of MHC class II molecules, exit from the resting state (G0) into the G1 phase of the cell cycle, and in the case of a strong antigenic stimulus, proliferation.

label

B-Cell Activation

Legacy Concept Name

B-Cell_Activation

Preferred_Name

B-Cell Activation

prefixIRI

NCIT:C19255

prefLabel

B-Cell Activation

Semantic_Type

Cell Function

UMLS_CUI

C1155003

subClassOf

http://purl.obolibrary.org/obo/NCIT_C40833

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