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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1904
http://purl.obolibrary.org/obo/NCIT_C1904
|
|---|---|
| Preferred Name | Topoisomerase-I Inhibitor |
| Definitions |
Any substance that inhibits topoisomerase-I, a topoisomerase that relieves torsional stress in a DNA molecule by cutting only one strand of the DNA double helix. Inhibition of topoisomerase-I causes DNA damage, inhibition of DNA replication, and apoptosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Any substance that inhibits topoisomerase-I, a topoisomerase that relieves torsional stress in a DNA molecule by cutting only one strand of the DNA double helix. Inhibition of topoisomerase-I causes DNA damage, inhibition of DNA replication, and apoptosis. |
|---|---|
| prefLabel | Topoisomerase-I Inhibitor
|
| label | Topoisomerase-I Inhibitor
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| CHEBI_ID | CHEBI:50276
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| code | C1904
|
| prefixIRI | NCIT:C1904
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| Preferred_Name | Topoisomerase-I Inhibitor
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| Legacy Concept Name | Topoisomerase-I_Inhibitor
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| type | |
| subClassOf | |
| Semantic_Type | Chemical Viewed Functionally
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| UMLS_CUI | C0594374
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