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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1871
http://purl.obolibrary.org/obo/NCIT_C1871
|
|---|---|
| Preferred Name | EGFR/HER1/HER2 Inhibitor PKI166 |
| Definitions |
A pyrrolo-pyrimidine epidermal growth factor receptor (EGFR) protein kinase inhibitor with anti-tumor activity. PKI-166 reversibly inhibits HER1 and HER2 tyrosine kinases, belong to the epidermal growth factor receptor family, thereby inhibiting tumor growth and metastasis.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A pyrrolo-pyrimidine epidermal growth factor receptor (EGFR) protein kinase inhibitor with anti-tumor activity. PKI-166 reversibly inhibits HER1 and HER2 tyrosine kinases, belong to the epidermal growth factor receptor family, thereby inhibiting tumor growth and metastasis. |
|---|---|
| prefLabel | EGFR/HER1/HER2 Inhibitor PKI166
|
| label | EGFR/HER1/HER2 Inhibitor PKI166
|
| code | C1871
|
| prefixIRI | NCIT:C1871
|
| in_subset | |
| Preferred_Name | EGFR/HER1/HER2 Inhibitor PKI166
|
| FDA_UNII_Code | 9RIE5HW38P
|
| Contributing_Source | FDA
|
| Maps_To | EGFR/HER1/HER2 Inhibitor PKI166
|
| CAS_Registry | 187724-61-4
|
| Legacy Concept Name | PKI166
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
|
| UMLS_CUI | C0915195
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| Delete | Subject | Author | Type | Created |
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