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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1866
http://purl.obolibrary.org/obo/NCIT_C1866
|
|---|---|
| Preferred Name | Epipodophyllotoxin Analog GL331 |
| Definitions |
An epipodophyllotoxin analogue possessing antineoplastic properties. GL331 binds to and inhibits topoisomerase II, resulting in the accumulation of single- or double-strand DNA breaks, the inhibition of DNA replication and transcription, and apoptotic cell death. (NCI)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An epipodophyllotoxin analogue possessing antineoplastic properties. GL331 binds to and inhibits topoisomerase II, resulting in the accumulation of single- or double-strand DNA breaks, the inhibition of DNA replication and transcription, and apoptotic cell death. (NCI) |
|---|---|
| prefLabel | Epipodophyllotoxin Analog GL331
|
| label | Epipodophyllotoxin Analog GL331
|
| code | C1866
|
| prefixIRI | NCIT:C1866
|
| in_subset | |
| Preferred_Name | Epipodophyllotoxin Analog GL331
|
| Maps_To | Epipodophyllotoxin Analog GL331
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| Legacy Concept Name | GL331
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0908996
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| Delete | Subject | Author | Type | Created |
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