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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1861
http://purl.obolibrary.org/obo/NCIT_C1861
|
|---|---|
| Preferred Name | Aclacinomycin B |
| Definitions |
An antineoplastic oligosaccharide anthracycline antibiotic isolated from the bacterium Streptomyces galilaeus. Aclacinomycin B intercalates into DNA and inhibits both the topoisomerase I and II enzymes, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An antineoplastic oligosaccharide anthracycline antibiotic isolated from the bacterium Streptomyces galilaeus. Aclacinomycin B intercalates into DNA and inhibits both the topoisomerase I and II enzymes, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. |
|---|---|
| prefLabel | Aclacinomycin B
|
| label | Aclacinomycin B
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| code | C1861
|
| prefixIRI | NCIT:C1861
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| in_subset | |
| Preferred_Name | Aclacinomycin B
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| FDA_UNII_Code | P8EJD9HI5K
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| Contributing_Source | FDA
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| Maps_To | Aclacinomycin B
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| CAS_Registry | 57596-79-9
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| NSC Number | 208735
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| Legacy Concept Name | Aclacinomycin_B
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
Antibiotic
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| UMLS_CUI | C0889093
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