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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
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| Preferred Name | Ursodiol | |
| Synonyms |
|
|
| Definitions |
A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese black bear liver, ursodiol has been used in the treatment of liver disease for centuries. This agent dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production and decreasing bile cholesterol. Ursodiol also reduces the absorption of cholesterol from the intestinal tract. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C1818 |
|
| Accepted_Therapeutic_Use_For |
Gallstone disolution; Primary biliary cirrhosis
|
|
| ALT_DEFINITION |
A drug that is used to dissolve gallstones in people who can't have surgery to remove them. It is also being studied in the prevention of colorectal cancer. Ursodiol belongs to the family of drugs called anticholelithics.
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| CAS_Registry |
128-13-2
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|
| CHEBI_ID |
CHEBI:9907
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|
| Chemical_Formula |
C24H40O4
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|
| code |
C1818
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|
| Contributing_Source |
CTRP FDA
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|
| definition |
A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese black bear liver, ursodiol has been used in the treatment of liver disease for centuries. This agent dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production and decreasing bile cholesterol. Ursodiol also reduces the absorption of cholesterol from the intestinal tract.
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|
| Display_Name |
Ursodiol
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|
| FDA_UNII_Code |
724L30Y2QR
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|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
| label |
Ursodiol
|
|
| Legacy Concept Name |
Ursodiol
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|
| NCI_Drug_Dictionary_ID |
306453
|
|
| NSC Number |
657950 683769
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|
| PDQ_Closed_Trial_Search_ID |
306453
|
|
| PDQ_Open_Trial_Search_ID |
306453
|
|
| Preferred_Name |
Ursodiol
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|
| prefixIRI |
NCIT:C1818
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|
| prefLabel |
Ursodiol
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|
| Semantic_Type |
Organic Chemical Pharmacologic Substance
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|
| UMLS_CUI |
C0042105
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|
| subClassOf |
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