Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17927
http://purl.obolibrary.org/obo/NCIT_C17927
|
|---|---|
| Preferred Name | Somatostatin Receptor Type 5 |
| Definitions |
Somatostatin receptor type 5 (364 aa, ~39 kDa) is encoded by the human SSTR5 gene. This protein is involved in somatostatin-dependent G protein-coupled receptor signaling.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Somatostatin receptor type 5 (364 aa, ~39 kDa) is encoded by the human SSTR5 gene. This protein is involved in somatostatin-dependent G protein-coupled receptor signaling. |
|---|---|
| prefLabel | Somatostatin Receptor Type 5
|
| label | Somatostatin Receptor Type 5
|
| code | C17927
|
| prefixIRI | NCIT:C17927
|
| OMIM_Number | 182455
|
| in_subset | |
| Display_Name | Somatostatin Receptor Type 5
|
| Preferred_Name | Somatostatin Receptor Type 5
|
| Contributing_Source | CTRP
|
| Swiss_Prot | P35346
|
| Legacy Concept Name | Somatostatin_Receptor-5
|
| DesignNote | Somatostatin receptor (SSTR) 5 and D2R GPCRs interact to create a novel receptor with enhanced activity; either ligand promotes heterodimerization. SSTR5 increases DNA synthesis, whereas SSTR2 inhibits DNA synthesis and cell proliferation. SSTR2 appears to antagonize SSTR5, and vice versa, suggesting a tissue-specific function and interaction between these receptors. SSTR5 is expressed in adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus.(OMIM 182455 and SWISS-PROT P35346)
|
| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Receptor
|
| UMLS_CUI | C0299636
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |