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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17923
http://purl.obolibrary.org/obo/NCIT_C17923
|
|---|---|
| Preferred Name | Receptor-Interacting Serine/Threonine-Protein Kinase 1 |
| Definitions |
Receptor-interacting serine/threonine-protein kinase 1 (671 aa, ~76 kDa) is encoded by the human RIPK1 gene. This protein plays a role in signaling that mediates inflammation, serine/threonine phosphorylation and cell death.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Receptor-interacting serine/threonine-protein kinase 1 (671 aa, ~76 kDa) is encoded by the human RIPK1 gene. This protein plays a role in signaling that mediates inflammation, serine/threonine phosphorylation and cell death. |
|---|---|
| prefLabel | Receptor-Interacting Serine/Threonine-Protein Kinase 1
|
| label | Receptor-Interacting Serine/Threonine-Protein Kinase 1
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| code | C17923
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| prefixIRI | NCIT:C17923
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| OMIM_Number | 603453
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| in_subset | |
| Display_Name | Receptor-Interacting Serine/Threonine-Protein Kinase 1
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| Preferred_Name | Receptor-Interacting Serine/Threonine-Protein Kinase 1
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| Contributing_Source | CTRP
|
| Swiss_Prot | Q13546
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| Legacy Concept Name | Receptor-Interacting_Serine-Threonine_Kinase-1
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| DesignNote | RIP1 interacts with the cytoplasmic domain of FAS, and with TNFR1 through the adaptor proteins TRADD and TRAFs 1, 2, and 3.
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
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| UMLS_CUI | C0297981
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