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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1783
http://purl.obolibrary.org/obo/NCIT_C1783
|
|---|---|
| Preferred Name | Piposulfan |
| Definitions |
An alkyl sulfonate with potential antineoplastic activity. Piposulfan alkylates DNA, thereby producing DNA interstrand crosslinks and DNA strand breaks and inhibiting DNA replication. This agent has been shown to exhibit antitumor activity in an animal model of prostate cancer. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | An alkyl sulfonate with potential antineoplastic activity. Piposulfan alkylates DNA, thereby producing DNA interstrand crosslinks and DNA strand breaks and inhibiting DNA replication. This agent has been shown to exhibit antitumor activity in an animal model of prostate cancer. (NCI04) |
|---|---|
| prefLabel | Piposulfan
|
| label | Piposulfan
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| code | C1783
|
| prefixIRI | NCIT:C1783
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| in_subset | |
| Preferred_Name | Piposulfan
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| FDA_UNII_Code | VY5DPN1TDU
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| Contributing_Source | FDA
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| Chemical_Formula | C12H22N2O8S2
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| Maps_To | Piposulfan
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| CAS_Registry | 2608-24-4
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| NSC Number | 47774
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| Legacy Concept Name | Piposulfan
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| UMLS_CUI | C0663942
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