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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17808
http://purl.obolibrary.org/obo/NCIT_C17808
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|---|---|
| Preferred Name | Dual Specificity Mitogen-Activated Protein Kinase Kinase 1 |
| Definitions |
Dual specificity mitogen-activated protein kinase kinase 1 (393 aa, ~43 kDa) is encoded by the human MAP2K1 gene. This protein plays a role in protein phosphorylation and the MAP kinase signal transduction pathway.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Dual specificity mitogen-activated protein kinase kinase 1 (393 aa, ~43 kDa) is encoded by the human MAP2K1 gene. This protein plays a role in protein phosphorylation and the MAP kinase signal transduction pathway. |
|---|---|
| prefLabel | Dual Specificity Mitogen-Activated Protein Kinase Kinase 1
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| label | Dual Specificity Mitogen-Activated Protein Kinase Kinase 1
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| code | C17808
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| prefixIRI | NCIT:C17808
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| OMIM_Number | 176872
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| in_subset | |
| Display_Name | Dual Specificity Mitogen-Activated Protein Kinase Kinase 1
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| Preferred_Name | Dual Specificity Mitogen-Activated Protein Kinase Kinase 1
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| Contributing_Source | CTRP
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| Swiss_Prot | Q02750
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| Legacy Concept Name | MAP2K1_Protein
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| DesignNote | A component of the RAS intracellular signaling pathway, MAP2K1 is a critical activating protein kinase of MAP kinase. p53 activates NFKB through a RAF/MAP2K1/p90(RSK) pathway. (Yu et al. Curr Biol 1998. 8:56-64 and OMIMI)
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
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| UMLS_CUI | C1434639
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