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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17802
http://purl.obolibrary.org/obo/NCIT_C17802
|
|---|---|
| Preferred Name | DNA Topoisomerase 2-Beta |
| Definitions |
DNA topoisomerase 2-beta (1626 aa, ~183 kDa) is encoded by the human TOP2B gene. This protein plays a role in DNA relaxation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | DNA topoisomerase 2-beta (1626 aa, ~183 kDa) is encoded by the human TOP2B gene. This protein plays a role in DNA relaxation. |
|---|---|
| prefLabel | DNA Topoisomerase 2-Beta
|
| label | DNA Topoisomerase 2-Beta
|
| code | C17802
|
| prefixIRI | NCIT:C17802
|
| OMIM_Number | 126431
|
| in_subset | |
| Display_Name | DNA Topoisomerase 2-Beta
|
| Preferred_Name | DNA Topoisomerase 2-Beta
|
| Contributing_Source | CTRP
|
| Swiss_Prot | Q02880
|
| Legacy Concept Name | Topoisomerase-II_Beta
|
| DesignNote | Both DNA topoisomerase 2-alpha and -beta proteins exhibit ATP-dependent strand passage activity, but they differ in several key aspects. The beta isoform relaxes DNA in a more progressive manner than the alpha isoform and also exhibits a higher optimal KCl requirement.
|
| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
|
| UMLS_CUI | C1504636
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