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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17801
http://purl.obolibrary.org/obo/NCIT_C17801
|
|---|---|
| Preferred Name | DNA Topoisomerase 2-Alpha |
| Definitions |
DNA topoisomerase 2-alpha (1531 aa, ~174 kDa) is encoded by the human TOP2A gene. This protein is involved in the modulation of DNA topology.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | DNA topoisomerase 2-alpha (1531 aa, ~174 kDa) is encoded by the human TOP2A gene. This protein is involved in the modulation of DNA topology. |
|---|---|
| label | DNA Topoisomerase 2-Alpha
|
| prefLabel | DNA Topoisomerase 2-Alpha
|
| Legacy Concept Name | Topoisomerase-II_Alpha
|
| in_subset | |
| Preferred_Name | DNA Topoisomerase 2-Alpha
|
| Display_Name | DNA Topoisomerase 2-Alpha
|
| Swiss_Prot | P11388
|
| DesignNote | Both DNA topoisomerase 2-alpha and -beta proteins exhibit ATP-dependent strand passage activity, but they differ in several key aspects. The beta isoform relaxes DNA in a more progressive manner than the alpha isoform and also exhibits a higher optimal KCl requirement.
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| prefixIRI | NCIT:C17801
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| Contributing_Source | CTRP
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| subClassOf | |
| code | C17801
|
| type | |
| OMIM_Number | 126430
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
|
| NCI_META_CUI | CL791262
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| Delete | Subject | Author | Type | Created |
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| No notes to display |