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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17766
http://purl.obolibrary.org/obo/NCIT_C17766
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|---|---|
| Preferred Name | Heat Shock Protein 90 |
| Definitions |
A family of structurally related proteins that play a role in cell signalling, protein folding and cellular stress responses. The members of this family are approximately 90 kDa.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A family of structurally related proteins that play a role in cell signalling, protein folding and cellular stress responses. The members of this family are approximately 90 kDa. |
|---|---|
| prefLabel | Heat Shock Protein 90
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| label | Heat Shock Protein 90
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| code | C17766
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| prefixIRI | NCIT:C17766
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| in_subset | |
| Display_Name | Heat Shock Protein 90
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| Preferred_Name | Heat Shock Protein 90
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| Contributing_Source | CTRP
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| Legacy Concept Name | Heat_Shock_Protein-90
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| DesignNote | The Heat Shock Protein 90 members HSP89-alpha and HSP89-beta are a class of cytoplasmic molecular chaperone homodimers that act in the signal transduction mechanism of steroid receptors and may have ATPase activity. CDC37 and HSP90 associate preferentially with CDK4 not bound to type D cyclins. HSPA8, HSP90A, CXCR4, and GDF5 on monocytes form an activation cluster after LPS ligation and are involved in LPS signal transduction. (OMIM 140571, Swiss-Prot P07900, P08238)
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| type | |
| subClassOf | |
| Semantic_Type | Amino Acid, Peptide, or Protein
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| UMLS_CUI | C0243044
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| No notes to display |