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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17698
http://purl.obolibrary.org/obo/NCIT_C17698
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|---|---|
| Preferred Name | Bcl-2-Like Protein 1 |
| Definitions |
Bcl-2-like protein 1 (233 aa, ~26 kDa) is encoded by the human BCL2L1 gene. This protein is involved in the modulation of apoptosis.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Bcl-2-like protein 1 (233 aa, ~26 kDa) is encoded by the human BCL2L1 gene. This protein is involved in the modulation of apoptosis. |
|---|---|
| prefLabel | Bcl-2-Like Protein 1
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| label | Bcl-2-Like Protein 1
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| code | C17698
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| prefixIRI | NCIT:C17698
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| OMIM_Number | 600039
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| in_subset | |
| Display_Name | Bcl-2-Like Protein 1
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| Preferred_Name | Bcl-2-Like Protein 1
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| Contributing_Source | CTRP
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| Swiss_Prot | Q07817
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| Legacy Concept Name | BCL-XL_Protein
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| DesignNote | Like bcl-2 bcl-xL acts as a repressor of apoptosis. bcl-xL mediates the closure of the mitochondrial porin channel VDAC and thus regulates the release of cytochrome c during apoptosis.
Bcl-2-like protein 1 has three isoforms that result from alternative splicing, Bcl-X(L), Bcl-X(S) and Bcl-X(beta). This concept describes the properties of the Bcl-X(L) isoform. (UniProt)
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| type | |
| subClassOf | |
| Semantic_Type | Amino Acid, Peptide, or Protein
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| UMLS_CUI | C0288330
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