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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17675
http://purl.obolibrary.org/obo/NCIT_C17675
|
|---|---|
| Preferred Name | Antigen KI-67 |
| Definitions |
Antigen KI-67 protein (3256 aa, ~359 kDa) is encoded by the human MKI67 gene. This protein is required for cell proliferation.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Antigen KI-67 protein (3256 aa, ~359 kDa) is encoded by the human MKI67 gene. This protein is required for cell proliferation. |
|---|---|
| label | Antigen KI-67
|
| prefLabel | Antigen KI-67
|
| Legacy Concept Name | Proliferation-Related-Ki-67_Antigen
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| in_subset | |
| Preferred_Name | Antigen KI-67
|
| Is_Value_For_GDC_Property | |
| Display_Name | Antigen KI-67
|
| Swiss_Prot | P46013
|
| DesignNote | Antigen KI-67 protein expression occurs during late G1, S, G2, and M phases of the cell cycle, while in cells in G0 phase the protein cannot be detected. The protein is located in the perinucleolar region during G1 phase. In the later phases it is detected throughout the nuclear interior, predominantly in the nuclear matrix. In mitosis, it is present on all chromosomes. (SwissProt)
Detection of Antigen KI-67 is used to locate proliferating cells in neoplastic diseases. (OMIM)
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| Maps_To | Ki67
|
| prefixIRI | NCIT:C17675
|
| Contributing_Source |
CTRP
GDC
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| subClassOf | |
| code | C17675
|
| type | |
| OMIM_Number | 176741
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| Semantic_Type |
Amino Acid, Peptide, or Protein
Immunologic Factor
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| NCI_META_CUI | CL963711
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| Delete | Subject | Author | Type | Created |
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