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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C1767
http://purl.obolibrary.org/obo/NCIT_C1767
|
|---|---|
| Preferred Name | Chaparrin |
| Definitions |
A quassinoid phytochemical isolated from Simaba cedron and other plant species with potential antineoplastic activity. Chaparrin is a mixture of compounds that includes flavonoids, antioxidants, and nordihydroguaiaretic acid (NDGA). NDGA is an antioxidant and lipoxygenase inhibitor that promotes cell differentiation, induces G1 phase cell-cycle arrest, and causes apoptosis in certain cancer cell lines. (NCI04)
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A quassinoid phytochemical isolated from Simaba cedron and other plant species with potential antineoplastic activity. Chaparrin is a mixture of compounds that includes flavonoids, antioxidants, and nordihydroguaiaretic acid (NDGA). NDGA is an antioxidant and lipoxygenase inhibitor that promotes cell differentiation, induces G1 phase cell-cycle arrest, and causes apoptosis in certain cancer cell lines. (NCI04) |
|---|---|
| label | Chaparrin
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| prefLabel | Chaparrin
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| Legacy Concept Name | Chaparrin
|
| in_subset | |
| Preferred_Name | Chaparrin
|
| Is_Value_For_GDC_Property | |
| Maps_To | Chaparrin
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| UMLS_CUI | C0630780
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| FDA_UNII_Code | YX31WC5SRV
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| prefixIRI | NCIT:C1767
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| Contributing_Source | FDA
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| subClassOf | |
| code | C1767
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| type | |
| NSC Number |
132794
79404
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| Semantic_Type |
Organic Chemical
Pharmacologic Substance
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| CAS_Registry | 4616-50-6
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