loading...| Preferred Name | Mitogen-Activated Protein Kinase 1 | |
| Synonyms |
|
|
| Definitions |
Mitogen-activated protein kinase 1 (390 aa, ~41 kDa) is encoded by the human MAPK1 gene. This protein plays a role in cell cycle regulation, signal transduction, transcriptional regulation and serine/threonine phosphorylation. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C17589 |
|
| code |
C17589 |
|
| Contributing_Source |
CTRP |
|
| definition |
Mitogen-activated protein kinase 1 (390 aa, ~41 kDa) is encoded by the human MAPK1 gene. This protein plays a role in cell cycle regulation, signal transduction, transcriptional regulation and serine/threonine phosphorylation. |
|
| DesignNote |
When MAPK1 is autophosphorylated or phosphorylated/activated by upstream kinases on threonine and tyrosine residues, it forms dimers with phosphorylated and unphosphorylated ERK partners, translocates to the nucleus and phosphorylates target transcription factors. |
|
| Display_Name |
Mitogen-Activated Protein Kinase 1 |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C116977 |
|
| label |
Mitogen-Activated Protein Kinase 1 |
|
| Legacy Concept Name |
Mitogen-Activated_Protein_Kinase-1 |
|
| OMIM_Number |
176948 |
|
| Preferred_Name |
Mitogen-Activated Protein Kinase 1 |
|
| prefixIRI |
NCIT:C17589 |
|
| prefLabel |
Mitogen-Activated Protein Kinase 1 |
|
| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme |
|
| Swiss_Prot |
P28482 |
|
| UMLS_CUI |
C2713871 |
|
| subClassOf |