Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17589
http://purl.obolibrary.org/obo/NCIT_C17589
|
|---|---|
| Preferred Name | Mitogen-Activated Protein Kinase 1 |
| Definitions |
Mitogen-activated protein kinase 1 (390 aa, ~41 kDa) is encoded by the human MAPK1 gene. This protein plays a role in cell cycle regulation, signal transduction, transcriptional regulation and serine/threonine phosphorylation.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Mitogen-activated protein kinase 1 (390 aa, ~41 kDa) is encoded by the human MAPK1 gene. This protein plays a role in cell cycle regulation, signal transduction, transcriptional regulation and serine/threonine phosphorylation. |
|---|---|
| label | Mitogen-Activated Protein Kinase 1
|
| prefLabel | Mitogen-Activated Protein Kinase 1
|
| Legacy Concept Name | Mitogen-Activated_Protein_Kinase-1
|
| in_subset | |
| Preferred_Name | Mitogen-Activated Protein Kinase 1
|
| Display_Name | Mitogen-Activated Protein Kinase 1
|
| Swiss_Prot | P28482
|
| DesignNote | When MAPK1 is autophosphorylated or phosphorylated/activated by upstream kinases on threonine and tyrosine residues, it forms dimers with phosphorylated and unphosphorylated ERK partners, translocates to the nucleus and phosphorylates target transcription factors.
|
| UMLS_CUI | C2713871
|
| prefixIRI | NCIT:C17589
|
| Contributing_Source | CTRP
|
| subClassOf | |
| code | C17589
|
| type | |
| OMIM_Number | 176948
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |