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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C17531
http://purl.obolibrary.org/obo/NCIT_C17531
|
|---|---|
| Preferred Name | Insulin-Like Growth Factor 1 Receptor |
| Definitions |
Insulin-like growth factor 1 receptor (1367 aa, ~155 kDa) is encoded by the human IGF1R gene. This protein is involved in cell proliferation and apoptosis inhibition.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | Insulin-like growth factor 1 receptor (1367 aa, ~155 kDa) is encoded by the human IGF1R gene. This protein is involved in cell proliferation and apoptosis inhibition. |
|---|---|
| prefLabel | Insulin-Like Growth Factor 1 Receptor
|
| label | Insulin-Like Growth Factor 1 Receptor
|
| code | C17531
|
| prefixIRI | NCIT:C17531
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| OMIM_Number | 147370
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| in_subset | |
| Display_Name | Insulin-Like Growth Factor 1 Receptor
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| Preferred_Name | Insulin-Like Growth Factor 1 Receptor
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| Contributing_Source | CTRP
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| Swiss_Prot | P08069
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| Legacy Concept Name | Insulin-Like_Growth_Factor-1_Receptor
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| DesignNote | Insulin-like growth factor-1 receptor is a membrane-bound protein, processed to form disulfide-linked alpha2/beta2 tetramer. It binds both insulin growth factors I and II. Ligand binding activates protein kinase activity, controls cell cycle progression and enhances cell survival.
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| type | |
| subClassOf | |
| Semantic_Type |
Amino Acid, Peptide, or Protein
Enzyme
Receptor
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| UMLS_CUI | C4044495
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| Delete | Subject | Author | Type | Created |
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| No notes to display |