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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C175306
http://purl.obolibrary.org/obo/NCIT_C175306
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|---|---|
| Preferred Name | Autologous TCRm-expressing T-cells ET140203 |
| Definitions |
A preparation of autologous T-lymphocytes that have been transduced with a lentiviral vector to express a T-cell receptor mimetic (TCRm) construct targeting as of yet undisclosed tumor associated antigen(s) (TAA), with potential immunomodulatory and antineoplastic activities. Upon administration, the autologous TCRm-expressing T-cells ET140203 specifically recognize and selectively bind to the as of yet undisclosed TAA(s). This results in cytotoxic T-lymphocyte (CTL)-mediated killing of tumor cells expressing the TAA(s).
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A preparation of autologous T-lymphocytes that have been transduced with a lentiviral vector to express a T-cell receptor mimetic (TCRm) construct targeting as of yet undisclosed tumor associated antigen(s) (TAA), with potential immunomodulatory and antineoplastic activities. Upon administration, the autologous TCRm-expressing T-cells ET140203 specifically recognize and selectively bind to the as of yet undisclosed TAA(s). This results in cytotoxic T-lymphocyte (CTL)-mediated killing of tumor cells expressing the TAA(s). |
|---|---|
| prefLabel | Autologous TCRm-expressing T-cells ET140203
|
| label | Autologous TCRm-expressing T-cells ET140203
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| NCI_META_CUI | CL1412643
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| PDQ_Closed_Trial_Search_ID | 803275
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| code | C175306
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| Has_Target | |
| prefixIRI | NCIT:C175306
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| in_subset |
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| Display_Name | Autologous TCRm-expressing T-cells ET140203
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| Preferred_Name | Autologous TCRm-expressing T-cells ET140203
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| Contributing_Source | CTRP
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| Maps_To | Autologous TCRm-expressing T-cells ET140203
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| NCI_Drug_Dictionary_ID | 803275
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 803275
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| Semantic_Type | Pharmacologic Substance
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