Preferred Name | Prostate-Specific Antigen | |
Synonyms |
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Definitions |
Prostate-specific antigen (261 aa, ~29 kDa) is encoded by the human KLK3 gene. This protein plays a role in both proteolysis and seminal fluid liquefaction. |
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ID |
http://purl.obolibrary.org/obo/NCIT_C17525 |
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ALT_DEFINITION |
A protein made by the prostate gland and found in the blood. Prostate-specific antigen blood levels may be higher than normal in men who have prostate cancer, benign prostatic hyperplasia (BPH), or infection or inflammation of the prostate gland. |
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code |
C17525 |
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Contributing_Source |
CTRP GDC |
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definition |
Prostate-specific antigen (261 aa, ~29 kDa) is encoded by the human KLK3 gene. This protein plays a role in both proteolysis and seminal fluid liquefaction. |
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DesignNote |
The serum level of PSA is used in diagnosis and monitoring of prostatic carcinoma, benign prostate hyperplasia, or infection or inflammation of the prostate. |
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Display_Name |
Prostate-Specific Antigen |
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in_subset |
http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C118168 http://purl.obolibrary.org/obo/NCIT_C157711 |
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Is_Value_For_GDC_Property | ||
label |
Prostate-Specific Antigen |
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Legacy Concept Name |
Prostate-Specific_Antigen |
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Maps_To |
Prostate-Specific Antigen (PSA) |
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OMIM_Number |
176820 |
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Preferred_Name |
Prostate-Specific Antigen |
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prefixIRI |
NCIT:C17525 |
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prefLabel |
Prostate-Specific Antigen |
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Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme |
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Swiss_Prot |
P07288 |
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UMLS_CUI |
C0138741 |
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subClassOf |