Link to this page
Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C174422
http://purl.obolibrary.org/obo/NCIT_C174422
|
|---|---|
| Preferred Name | Anti-VEGFR2 Monoclonal Antibody MSB0254 |
| Definitions |
A humanized monoclonal antibody directed against human vascular endothelial growth factor receptor 2 (VEGFR-2; VEGFR2) with potential anti-angiogenesis and antineoplastic activities. Upon administration, anti-VEGFR2 monoclonal antibody MSB0254 specifically binds to and inhibits VEGFR2, which may inhibit tumor angiogenesis and tumor cell proliferation. VEGFR2, a tyrosine-protein kinase that plays an essential role in angiogenesis and the proliferation, survival, migration and differentiation of endothelial cells, is overexpressed in certain tumor types.
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A humanized monoclonal antibody directed against human vascular endothelial growth factor receptor 2 (VEGFR-2; VEGFR2) with potential anti-angiogenesis and antineoplastic activities. Upon administration, anti-VEGFR2 monoclonal antibody MSB0254 specifically binds to and inhibits VEGFR2, which may inhibit tumor angiogenesis and tumor cell proliferation. VEGFR2, a tyrosine-protein kinase that plays an essential role in angiogenesis and the proliferation, survival, migration and differentiation of endothelial cells, is overexpressed in certain tumor types. |
|---|---|
| prefLabel | Anti-VEGFR2 Monoclonal Antibody MSB0254
|
| label | Anti-VEGFR2 Monoclonal Antibody MSB0254
|
| NCI_META_CUI | CL1411984
|
| PDQ_Closed_Trial_Search_ID | 802274
|
| code | C174422
|
| prefixIRI | NCIT:C174422
|
| in_subset | |
| Preferred_Name | Anti-VEGFR2 Monoclonal Antibody MSB0254
|
| Maps_To | Anti-VEGFR2 Monoclonal Antibody MSB0254
|
| NCI_Drug_Dictionary_ID | 802274
|
| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 802274
|
| Semantic_Type |
Amino Acid, Peptide, or Protein
Pharmacologic Substance
|
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |