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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C174397
http://purl.obolibrary.org/obo/NCIT_C174397
|
|---|---|
| Preferred Name | Allogeneic Anti-CD20 CAR T-cells LUCAR-20S |
| Definitions |
A preparation of donor-derived T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD20 (cluster of differentiation 20), with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic anti-CD20 CAR T-cells LUCAR-20S specifically recognize and kill CD20-expressing tumor cells. The CD20 antigen, a non-glycosylated cell surface phosphoprotein, is a B-cell specific cell surface antigen expressed in B-cell lineage malignancies.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A preparation of donor-derived T-lymphocytes that have been genetically modified to express a chimeric antigen receptor (CAR) targeting the tumor-associated antigen (TAA) CD20 (cluster of differentiation 20), with potential immunostimulating and antineoplastic activities. Upon administration, allogeneic anti-CD20 CAR T-cells LUCAR-20S specifically recognize and kill CD20-expressing tumor cells. The CD20 antigen, a non-glycosylated cell surface phosphoprotein, is a B-cell specific cell surface antigen expressed in B-cell lineage malignancies. |
|---|---|
| label | Allogeneic Anti-CD20 CAR T-cells LUCAR-20S
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| prefLabel | Allogeneic Anti-CD20 CAR T-cells LUCAR-20S
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| in_subset | |
| Preferred_Name | Allogeneic Anti-CD20 CAR T-cells LUCAR-20S
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| Is_Value_For_GDC_Property | |
| Maps_To | Allogeneic Anti-CD20 CAR T-cells LUCAR-20S
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| PDQ_Open_Trial_Search_ID | 802323
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| prefixIRI | NCIT:C174397
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| NCI_Drug_Dictionary_ID | 802323
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| subClassOf | |
| code | C174397
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| type | |
| PDQ_Closed_Trial_Search_ID | 802323
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| Semantic_Type | Pharmacologic Substance
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| NCI_META_CUI | CL1411949
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