loading...| Preferred Name |
Glucose-6-Phosphate Isomerase |
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| Synonyms |
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| Definitions |
Glucose-6-phosphate isomerase (558 aa, ~63 kDa) is encoded by the human GPI gene. This protein is involved in glycolysis in as a cytoplasmic homodimer and has a secreted monomeric form that either exhibits cytokine activity or can function as a neurotrophic factor. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C17428 |
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| code |
C17428 |
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| definition |
Glucose-6-phosphate isomerase (558 aa, ~63 kDa) is encoded by the human GPI gene. This protein is involved in glycolysis in as a cytoplasmic homodimer and has a secreted monomeric form that either exhibits cytokine activity or can function as a neurotrophic factor. |
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| DesignNote |
The enzymatically active form of glucose-6-phosphate isomerase (GPI) is a cytosolic homodimer. GPI expresses cytokine activity when secreted as a monomer. (UniProt) |
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| label |
Glucose-6-Phosphate Isomerase |
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| Legacy Concept Name |
Glucose_Phosphate_Isomerase |
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| OMIM_Number |
172400 |
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| Preferred_Name |
Glucose-6-Phosphate Isomerase |
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| prefixIRI |
NCIT:C17428 |
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| prefLabel |
Glucose-6-Phosphate Isomerase |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Enzyme |
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| Swiss_Prot |
P06744 |
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| UMLS_CUI |
C0085144 |
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| subClassOf |