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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C174121
http://purl.obolibrary.org/obo/NCIT_C174121
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|---|---|
| Preferred Name | Anti-HER2 Monoclonal Antibody B002 |
| Definitions |
A humanized monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2; ErbB2; HER-2), with potential antineoplastic activity. Upon administration, anti-HER2 monoclonal antibody B002 targets and binds to HER2 on HER2-expressing tumor cells. This prevents HER2-mediated signaling and may lead to antitumor activity. HER2, a tyrosine kinase receptor, is overexpressed by many cancer cell types.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A humanized monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2; ErbB2; HER-2), with potential antineoplastic activity. Upon administration, anti-HER2 monoclonal antibody B002 targets and binds to HER2 on HER2-expressing tumor cells. This prevents HER2-mediated signaling and may lead to antitumor activity. HER2, a tyrosine kinase receptor, is overexpressed by many cancer cell types. |
|---|---|
| prefLabel | Anti-HER2 Monoclonal Antibody B002
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| label | Anti-HER2 Monoclonal Antibody B002
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| NCI_META_CUI | CL1407790
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| PDQ_Closed_Trial_Search_ID | 802228
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| code | C174121
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| prefixIRI | NCIT:C174121
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| in_subset | |
| Preferred_Name | Anti-HER2 Monoclonal Antibody B002
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| Maps_To | Anti-HER2 Monoclonal Antibody B002
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| NCI_Drug_Dictionary_ID | 802228
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 802228
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| Semantic_Type | Pharmacologic Substance
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