Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Id http://purl.obolibrary.org/obo/NCIT_C1740
http://purl.obolibrary.org/obo/NCIT_C1740
Preferred Name

Aromatase Inhibitor
Definitions
Any substance that inhibits aromatase, an enzyme responsible for the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Inhibition of aromatase results in the suppression of estrogen-regulated processes.
Type http://www.w3.org/2002/07/owl#Class

All Properties

definition

Any substance that inhibits aromatase, an enzyme responsible for the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Inhibition of aromatase results in the suppression of estrogen-regulated processes.
prefLabel
Aromatase Inhibitor
label
Aromatase Inhibitor
CHEBI_ID
CHEBI:50790
code
C1740
prefixIRI
NCIT:C1740
in_subset
Display_Name
Aromatase Inhibitor
Preferred_Name
Aromatase Inhibitor
Contributing_Source
CTRP
Legacy Concept Name
Aromatase_Inhibitor
type
ALT_DEFINITION
A drug that prevents the formation of estradiol, a female hormone, by interfering with an aromatase enzyme. Aromatase inhibitors are used as a type of hormone therapy for postmenopausal women who have hormone-dependent breast cancer.
subClassOf
Semantic_Type
Chemical Viewed Functionally
UMLS_CUI
C0593802
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