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Biological and Environmental Research Ontology
Last uploaded:
December 23, 2022
| Id | http://purl.obolibrary.org/obo/NCIT_C173877
http://purl.obolibrary.org/obo/NCIT_C173877
|
|---|---|
| Preferred Name | Taniraleucel |
| Definitions |
A population of cryopreserved, off-the-shelf (OTS) allogeneic natural killer (NK) cells derived from human placental hematopoietic stem cells (HSCs) and expressing the CD56 surface antigen and exhibiting a lack of CD3, with potential immunomodulating, antineoplastic and antiviral activities. Upon infusion of taniraleucel, these cells are able to recognize tumor cells as well as virally-infected cells, secrete perforins, granzymes and cytokines, and induce apoptosis in tumor and virally-infected cells.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| definition | A population of cryopreserved, off-the-shelf (OTS) allogeneic natural killer (NK) cells derived from human placental hematopoietic stem cells (HSCs) and expressing the CD56 surface antigen and exhibiting a lack of CD3, with potential immunomodulating, antineoplastic and antiviral activities. Upon infusion of taniraleucel, these cells are able to recognize tumor cells as well as virally-infected cells, secrete perforins, granzymes and cytokines, and induce apoptosis in tumor and virally-infected cells. |
|---|---|
| prefLabel | Taniraleucel
|
| label | Taniraleucel
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| NCI_META_CUI | CL1407641
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| PDQ_Closed_Trial_Search_ID | 802398
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| code | C173877
|
| prefixIRI | NCIT:C173877
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| in_subset |
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| Display_Name | Taniraleucel
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| Preferred_Name | Taniraleucel
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| FDA_UNII_Code | XO25H8E4QP
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| Contributing_Source |
CTRP
FDA
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| Maps_To | Allogeneic CD56-positive CD3-negative Natural Killer Cells CYNK-001
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| NCI_Drug_Dictionary_ID | 802398
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| type | |
| Is_Value_For_GDC_Property | |
| subClassOf | |
| PDQ_Open_Trial_Search_ID | 802398
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| Semantic_Type |
Pharmacologic Substance
Cell
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| Delete | Subject | Author | Type | Created |
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